Institution: UNITO. Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Tasks in the project: Tracy Ann Williams is with Paolo Mulatero the UNITO group leader involved in WP2 and WP4-6. 

WP2 & WP4-6: Contribution: see Paolo Mulatero

Biography:

Dr. Tracy Ann Williams is a research scientist at the Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Turin, Italy. She obtained her PhD degree in Biochemistry and Molecular Biology, University of Leeds, UK and was awarded a Royal Society of Great Britain fellowship for her post-doctoral studies at the Collège de France, Paris, France. Dr. Williams subsequently moved to the University of Turin, Italy obtaining an EMBO long-term fellowship and a Marie-Curie research training grant before obtaining her current position. Her research focuses on the underlying biology of primary aldosteronism. In particular, the identification of factors or elucidation of mechanisms that trigger and sustain the aldosterone excess in this disorder.

 

Main publications:

Williams TA, Dietz SA, Theodoropoulou M, Riester A, Fischer E, Burrello J, Treitl M, Geyer L, Veglio F, Bidlingmaier M, Schopohl J, Beuschlein F, Mulatero P, Reincke M. Co-existing prolactinoma and primary aldosteronism - is there a pathophysiological link? J Clin Endocrinol Metab. 2015; in press

Williams TA, Mulatero P, Bidlingmaier M, Beuschlein F, Reincke M. Genetic and potential immune triggers of primary aldosteronism. Hypertension 2015;66:248-253.

 Williams TA, Monticone S, Schack VR, Stindl J, Burrello J, Buffolo F, Annaratone L, Castellano I, Beuschlein F, Reincke M, Lucatello B, Ronconi V, Fallo F, Bernini G, Maccario M, Giacchetti G, Veglio F, Warth R, Vilsen B, Mulatero P. Somatic ATP1A1, ATP2B3 and KCNJ5 mutations in aldosterone-producing adenomas. Hypertension 2014; 63: 188-195.

 Williams TA, Monticone S, Crudo V, Warth R, Veglio F and Mulatero P.

VSNL1 is up-regulated in aldosterone-producing adenomas harbouring KCNJ5 mutations and protects from calcium-induced apoptosis in vitro. Hypertension 2012; 59: 833-839.

 Williams TA, Monticone S, Morello F, Liew CC, Mengozzi G, Pilon C, Asioli S, Sapino A, Veglio F, Mulatero P. Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro. Hypertension 2010;55:1468-1475.

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People

Scientific Coordinator: Dr Maria -Christina Zennaro, Head of INSERM U970 team 14: Genetic mechanisms of aldosterone-related disorders. maria-christina.zennaro@inserm.fr

Project Manager (INSERM-Transfert): Catherine Clusel catherine.clusel@inserm-transfert.fr

Project Manager (INSERM-Transfert): Kristina Fiedler kristina.fiedler@inserm-transfert.fr

More contact details here

Places

Paris Cardiovascular Research Center (PARCC), European Georges Pompidou Hospital, 56 rue Leblanc, 75015 Paris, France

INSERM-Transfert, Paris Biopark, 7 rue Watt, 75013 Paris, France

Maps

European Georges Pompidou Hospital


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